Antagonistic Effects of Doublecortin and MARK2/Par-1 in the Developing Cerebral Cortex
نویسندگان
چکیده
منابع مشابه
Antagonistic effects of doublecortin and MARK2/Par-1 in the developing cerebral cortex.
Abnormal neuronal migration is manifested in brain malformations such as lissencephaly. The impairment in coordinated cell motility likely reflects a faulty mechanism of cell polarization or coupling between polarization and movement. Here we report on the relationship between the polarity kinase MARK2/Par-1 and its substrate, the well-known lissencephaly-associated gene doublecortin (DCX), dur...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2008
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.2363-08.2008